Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36575 | 0.82 | — | — | |
| SCHEMBL536550 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL1007846 | 0.80 | — | — | |
| SCHEMBL28815407 | 0.75 | LMNA (0.44) | LMNATDP1GAASMN1; SMN2HCRTR1 | |
| Acrylamide SCHEMBL11786592 | 0.70 | LMNA (0.40) | LMNATDP1GAASMN1; SMN2HCRTR1 | |
| Quinoline SCHEMBL28065865 | 0.69 | ALDH1A1 (0.52) | LMNATDP1GAASMN1; SMN2HCRTR1 | |
| Imidazole SCHEMBL11036126 | 0.68 | ALDH1A1 (0.42) | LMNATDP1GAASMN1; SMN2HCRTR1 | |
| SCHEMBL5164997 | 0.68 | LMNA (0.38) | LMNATDP1GAASMN1; SMN2CYP3A4 | |
| Acrylic Acid SCHEMBL11792959 | 0.67 | LMNA (0.37) | LMNATDP1GAASMN1; SMN2HCRTR1 | |
| Acrylic Acid Methyl Ester SCHEMBL15637879 | 0.67 | TDP1 (0.37) | LMNATDP1GAASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300289-B1 | GRAFT COPOLYMER REACTION PRODUCT WITH NITROGENOUS ETHYLENICALLY UNSATURATED ALIPHATIC OR AROMATIC COMPOUNDS | CASTROL LIMITED (GB) | 2001-10-09 | — | — | US | claimed |