SCHEMBL7995045

SCHEMBL7995045

CCCCC(CC)Cc1cc(O)cc(Cl)c1Cl

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.38
HPGD P15428 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 7/20 0.38
MAPK1 P28482 2/20 0.36
TSHR P16473 3/20 0.35
GLA P06280 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
ADRB2 P07550 4/20 0.33
CA2 P00918 3/20 0.33
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763520 0.77 ALDH1A1 (0.39) CYP3A4ALDH1A1MAPK1TSHRGLA
SCHEMBL30933046 0.76 ALDH1A1 (0.38) CYP3A4ALDH1A1MAPK1TSHRGLA
SCHEMBL11328765 0.75 TYR (0.45) CYP3A4ALDH1A1TSHRHTTTDP1
SCHEMBL19433117 0.74 PTGS2 (0.50) CYP3A4ALDH1A1TSHRTDP1ADRB2
SCHEMBL7995859 0.72 PTGS2 (0.53) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL7995041 0.72 PTGS2 (0.53) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL7994866 0.72 PTGS2 (0.53) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL7994963 0.72 PTGS2 (0.53) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL7992788 0.72 PTGS2 (0.53) CYP3A4HPGDCRHBPCRHR2HSD17B10
SCHEMBL11039409 0.72 TYR (0.57) CYP3A4HPGDHSD17B10ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6277537-B1 PHENOLIC COMPOUND EASTMAN KODAK COMPANY 2001-08-21 US claimed
US-5512410-A Heat image separation with phenolic thermal solvents and dye releasing couplers EASTMAN KODAK COMPANY (US) 1996-04-30 US claimed
US-6277537-B1 PHENOLIC COMPOUND EASTMAN KODAK COMPANY 2001-08-21 US disclosed
EP-0545433-B1 Thermal solvents for dye diffusion in image separation systems EASTMAN KODAK CO (US) 1999-03-17 EP disclosed
US-5512410-A Heat image separation with phenolic thermal solvents and dye releasing couplers EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed
US-5356750-A Dye releasing couplers for heat image separation systems EASTMAN KODAK COMPANY (US) 1994-10-18 US disclosed