SCHEMBL8763520

SCHEMBL8763520

CCCCC(CC)Cc1cc(Cl)c(O)cc1O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.39
MAPK1 P28482 2/20 0.36
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
BCL2L1 Q07817 1/20 0.34
TSHR P16473 3/20 0.34
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
CA2 P00918 3/20 0.33
TYR P14679 1/20 0.33
GLA P06280 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763525 0.87 ALOX15 (0.40) ALDH1A1MAPK1LMNATDP1TSHR
SCHEMBL8764403 0.81 ALDH1A1 (0.39) ALDH1A1MAPK1LMNATDP1BCL2L1
SCHEMBL7995045 0.77 CYP3A4 (0.38) ALDH1A1MAPK1LMNATDP1TSHR
SCHEMBL11328765 0.76 TYR (0.45) ALDH1A1LMNATDP1TSHRCYP3A4
SCHEMBL11039409 0.76 TYR (0.57) ALDH1A1LMNATDP1TSHRCYP3A4
SCHEMBL27543288 0.75 TYR (0.40) ALDH1A1MAPK1LMNATDP1BCL2L1
SCHEMBL2483269 0.75 BCL2L1 (0.38) ALDH1A1MAPK1LMNATDP1BCL2L1
SCHEMBL68685 0.74 TYR (0.53) ALDH1A1MAPK1TDP1TSHRCYP3A4
SCHEMBL10686684 0.74 TSHR (0.35) ALDH1A1LMNATDP1BCL2L1TSHR
SCHEMBL8763419 0.73 ALOX5 (0.53) TDP1BCL2L1TSHRCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623339-B1 Use of 4-,4- and 5-, or 4- and 6-substituted derivatives of resorcin in cosmetic or dermopharmaceutical compositions for depigmentation OREAL (FR) 1997-07-23 EP claimed