Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11328765 | 0.87 | TYR (0.45) | TYRHTTCYP3A4MAPTALOX5 | |
| SCHEMBL27543288 | 0.86 | TYR (0.40) | TYRHTTCYP3A4MAPTALOX5 | |
| SCHEMBL490521 | 0.81 | LMNA (0.51) | TYRHTTCYP3A4MAPTALOX5 | |
| SCHEMBL105941 | 0.80 | LMNA (0.51) | HTTCYP3A4TSHRTDP1KDM4E | |
| SCHEMBL30763513 | 0.80 | LMNA (0.51) | HTTCYP3A4TSHRTDP1KDM4E | |
| SCHEMBL4227451 | 0.79 | MGLL (0.44) | TYRHTTCYP3A4MAPTALOX5 | |
| SCHEMBL12610588 | 0.79 | ALDH1A1 (0.41) | TYRHTTCYP3A4TSHRTDP1 | |
| SCHEMBL28293994 | 0.79 | LMNA (0.50) | HTTCYP3A4TSHRTDP1KDM4E | |
| SCHEMBL128530 | 0.78 | HTT (0.44) | HTTCYP3A4TSHRKDM4EALDH1A1 | |
| SCHEMBL8764403 | 0.76 | ALDH1A1 (0.39) | TYRHTTCYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129781-B2 | Agent for hair deforming treatment | KAO CORPORATION (JP) | 2021-09-28 | — | — | US | disclosed |
| US-11045402-B2 | Hair cosmetic composition | KAO CORPORATION (JP) | 2021-06-29 | — | — | US | disclosed |
| US-10959925-B2 | Hair cosmetic composition | KAO CORPORATION (JP) | 2021-03-30 | — | — | US | disclosed |
| EP-3228302-B1 | HAIR DEFORMATION TREATMENT AGENT | KAO CORP (JP) | 2020-09-02 | — | — | EP | disclosed |
| CN-106999382-B | Hair deforming agent | 花王株式会社 | 2020-07-10 | — | — | CN | disclosed |
| CN-106999380-B | Hair deforming agent | 花王株式会社 | 2020-05-05 | — | — | CN | disclosed |
| US-20190290564-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2019-09-26 | — | — | US | disclosed |
| US-20190254943-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2019-08-22 | — | — | US | disclosed |
| US-20190224093-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2019-07-25 | — | — | US | disclosed |
| US-20190125052-A1 | METHOD FOR TREATING HAIR | KAO CORPORATION (JP) | 2019-05-02 | — | — | US | disclosed |
| WO-2017207786-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017207767-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017207799-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2017-12-07 | — | — | WO | disclosed |
| EP-3228300-A1 | HAIR DEFORMATION TREATMENT AGENT | Kao Corporation (JP) | 2017-10-11 | — | — | EP | disclosed |
| EP-3228302-A1 | HAIR DEFORMATION TREATMENT AGENT | Kao Corporation (JP) | 2017-10-11 | — | — | EP | disclosed |
| CN-106999382-A | Hair deformation process agent | 花王株式会社 | 2017-08-01 | — | — | CN | disclosed |
| CN-106999380-A | Hair deforming agent | 花王株式会社 | 2017-08-01 | — | — | CN | disclosed |
| EP-0061015-B1 | PROCESS FOR THE PREPARATION OF A 2-ALKYLPHENOL | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1984-04-11 | — | — | EP | disclosed |
| US-4419529-A | Process for the preparation of a 2-alkylphenol | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1983-12-06 | — | — | US | disclosed |
| EP-0061015-A1 | Process for the preparation of a 2-alkylphenol | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1982-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11045402-B2 | Hair cosmetic composition | CUTA, GRHPR, POLR1C | TYR 6/4885HTT 46/4885CYP3A4 1895/4885 |
| US-10959925-B2 | Hair cosmetic composition | CUTA, POLR1C, GRHPR | TYR 4/4885HTT 137/4885CYP3A4 1786/4885 |
| US-20190254943-A1 | HAIR COSMETIC COMPOSITION | CUTA, POLR1C, GRHPR | TYR 4/4885HTT 137/4885CYP3A4 1786/4885 |
| US-20190125052-A1 | METHOD FOR TREATING HAIR | GRHPR, TYR, POLR1C | TYR 2/4885HTT 433/4885CYP3A4 848/4885 |
| US-20190224093-A1 | HAIR COSMETIC COMPOSITION | CUTA, GRHPR, POLR1C | TYR 6/4885HTT 46/4885CYP3A4 1895/4885 |
| US-11129781-B2 | Agent for hair deforming treatment | GRHPR, SLC26A4, COL1A1 | TYR 98/4885HTT 208/4885CYP3A4 3291/4885 |
| US-20190290564-A1 | HAIR COSMETIC COMPOSITION | GRHPR, POLR1C, TYR | TYR 3/4885HTT 136/4885CYP3A4 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.