Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 9/20 | 0.44 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11705152 | 0.73 | RAB9A (0.68) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL7993584 | 0.73 | NPC1 (0.56) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL11705140 | 0.71 | RAB9A (0.68) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL7993421 | 0.66 | NPC1 (0.57) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL24169384 | 0.65 | ESR1 (0.56) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL6929891 | 0.65 | ALDH1A1 (0.60) | RAB9ANPC1MEN1KMT2AOPRK1 | |
| SCHEMBL11700747 | 0.64 | NPC1 (0.69) | RAB9ANPC1PKMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7996765 | 0.64 | MAOB (0.59) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL11703485 | 0.63 | RAB9A (0.73) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL29420092 | 0.63 | NPC1 (0.81) | RAB9ANPC1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070705-A1 | 2-ACYLAMINOBENZIMIDAZOLE DERIVATIVES FOR TREATING GLAUCOMA | ALCON, INC. (CH) | 2001-09-27 | — | — | WO | disclosed |