Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 16/20 | 0.54 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.50 |
| ▸ | FKBP5 | Q13451 | 2/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220783 | 1.00 | FKBP1A (0.54) | FKBP1AFKBP4FKBP5ABCC1MTOR | |
| SCHEMBL7984949 | 0.93 | FKBP1A (0.61) | FKBP1AFKBP4FKBP5ABCC1HTT | |
| SCHEMBL7995090 | 0.89 | FKBP1A (0.57) | FKBP1AFKBP4FKBP5MTOR | |
| SCHEMBL7995095 | 0.89 | FKBP1A (0.57) | FKBP1AFKBP4FKBP5MTOR | |
| SCHEMBL7984933 | 0.77 | MAPT (0.46) | FKBP1AFKBP4FKBP5MTOR | |
| SCHEMBL5847498 | 0.74 | FKBP1A (0.43) | FKBP1AFKBP4FKBP5MTOR | |
| SCHEMBL7469652 | 0.69 | FKBP1A (0.67) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL7463760 | 0.69 | FKBP1A (0.62) | FKBP1AFKBP4FKBP5ABCC1 | |
| SCHEMBL30147174 | 0.67 | TSHR (0.49) | HTT | |
| SCHEMBL16310240 | 0.67 | FKBP1A (0.89) | FKBP1AFKBP4FKBP5ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000046222-A1 | HETEROAROMATIC COMPOUNDS WITH NEURONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-08-10 | — | — | WO | claimed |