Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.60 |
| ▸ | APAF1 | O14727 | 2/20 | 0.60 |
| ▸ | NSD2 | O96028 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.57 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP2 | O95551 | 1/20 | 0.52 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991450 | 0.93 | CASP3 (0.65) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL7991616 | 0.88 | CASP3 (0.64) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL23458036 | 0.88 | CASP3 (0.76) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL23458028 | 0.86 | CASP3 (0.78) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL7991749 | 0.86 | CASP3 (0.61) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL7987788 | 0.83 | MAOB (0.50) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL7989463 | 0.82 | CASP3 (0.61) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL7991698 | 0.81 | CASP3 (0.57) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL21690569 | 0.78 | CASP3 (0.77) | CASP3SENP6SENP8SENP7APAF1 | |
| SCHEMBL7995202 | 0.78 | P2RY14 (0.52) | L3MBTL1KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055117-A1 | NOVEL ISOQUINOLINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2001-08-02 | — | — | WO | disclosed |