SCHEMBL7995452

SCHEMBL7995452

O=C(O)CNNc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABAT P80404 1/20 0.50
ALOX5 P09917 2/20 0.48
TSHR P16473 2/20 0.48
CYP3A4 P08684 1/20 0.48
ALDH1A1 P00352 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
CTSD P07339 1/20 0.48
PTGS2 P35354 1/20 0.47
GAA P10253 7/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
TP53 P04637 1/20 0.44
EPHX1 P07099 1/20 0.44
EPHX2 P34913 1/20 0.44
CDK9 P50750 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
ALOX12 P18054 1/20 0.44
CYP2C19 P33261 1/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
PTPN7 P35236 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10725547 0.88 MMP12 (0.50) TSHRALDH1A1GAASMN1; SMN2MAPT
SCHEMBL10346557 0.83 ALOX5 (0.55) ALOX5TSHRCYP3A4ALDH1A1TDP1
SCHEMBL19720271 0.82 L3MBTL1 (0.47) ABATALOX5TSHRCYP3A4ALDH1A1
SCHEMBL8858556 0.79 MAPT (0.53) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL10439096 0.79 MAPK1 (0.56) ALDH1A1MAPTKDM4E
SCHEMBL27464764 0.78 CA12 (0.50) ALOX5TSHRCYP3A4ALDH1A1TDP1
SCHEMBL16763415 0.78 ALDH1A1 (0.55) ALOX5TSHRCYP3A4ALDH1A1TDP1
SCHEMBL31123427 0.77 SAE1 (0.47) TSHRALDH1A1MAPTMEN1KMT2A
SCHEMBL41828 0.76 ABAT (0.53) ABATTSHRALDH1A1GAASMN1; SMN2
SCHEMBL1330698 0.76 ABAT (0.53) ABATTSHRALDH1A1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0732944-A4 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION GEN HOSPITAL CORP (US) 2000-06-07 EP claimed
US-5792444-A ADMINISTERING LABELED CHEMOTACTIC PEPTIDE WHICH ACCUMULATES AT SITE OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1998-08-11 US claimed
EP-0732944-A1 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1996-09-25 EP claimed
WO-1995011045-A1 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1995-04-27 WO claimed
US-9929348-B2 Organic semiconductor composition comprising organic semiconductor material and polymer compound FUJIFILM CORPORATION (JP) 2018-03-27 US disclosed
US-9343594-B2 Conductive composition, conductive member and production method thereof, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2016-05-17 US disclosed
US-9343594-B2 Conductive composition, conductive member and production method thereof, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2016-05-17 US disclosed
US-20160064674-A1 ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed
US-20160064674-A1 ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed
CN-1077439-C Labeled chemotactic peptides for imaging of sites of infection or inflammation lesions GEN HOSPITAL CORP (US) 2002-01-09 CN disclosed
EP-0732944-A4 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION GEN HOSPITAL CORP (US) 2000-06-07 EP disclosed
US-5792444-A ADMINISTERING LABELED CHEMOTACTIC PEPTIDE WHICH ACCUMULATES AT SITE OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1998-08-11 US disclosed
CN-1141002-A Labeled chemotactic peptides for imaging of sites of infection or inflammation lesions GEN HOSPITAL CORP (US) 1997-01-22 CN disclosed
EP-0732944-A1 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1996-09-25 EP disclosed
WO-1995011045-A1 LABELED CHEMOTACTIC PEPTIDES TO IMAGE FOCAL SITES OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1995-04-27 WO disclosed