Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 8/20 | 0.44 |
| ▸ | MMP2 | P08253 | 7/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 6/20 | 0.41 |
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | MMP14 | P50281 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29307827 | 0.76 | ALDH1A1 (0.41) | KISS1RALDH1A1 | |
| SCHEMBL23901238 | 0.76 | ALDH1A1 (0.42) | MMEALDH1A1TDP1 | |
| SCHEMBL8000058 | 0.76 | ALDH1A1 (0.43) | MMEMMP9MMP2MMP8KISS1R | |
| SCHEMBL23643228 | 0.73 | ALDH1A1 (0.39) | MMEALDH1A1TDP1 | |
| SCHEMBL14985792 | 0.73 | SLC7A5 (0.48) | KISS1RALDH1A1 | |
| SCHEMBL5672721 | 0.72 | KISS1R (0.61) | MMEMMP9MMP2MMP8KISS1R | |
| SCHEMBL20792907 | 0.71 | ALDH1A1 (0.39) | MMEMMP9MMP2MMP8KISS1R | |
| SCHEMBL14804658 | 0.70 | ALDH1A1 (0.36) | MMEMMP8KISS1RALDH1A1 | |
| SCHEMBL4288816 | 0.70 | MMP2 (0.63) | MMEMMP9MMP2MMP8MMP1 | |
| SCHEMBL19483401 | 0.70 | ALDH1A1 (0.50) | MMEMMP9MMP2MMP8KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113320-A1 | MMP INHIBITOR | 株式会社ヤクルト本社 (JP) | 2009-09-17 | — | — | WO | disclosed |