SCHEMBL7995645

SCHEMBL7995645

CSCc1ccc(C(=O)c2ccc(Br)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.57
NPC1 O15118 4/20 0.57
LMNA P02545 5/20 0.50
MAPT P10636 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
MAPK1 P28482 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
SRD5A2 P31213 1/20 0.49
EPHX1 P07099 2/20 0.47
SMN1; SMN2 Q16637 4/20 0.46
KDM4E B2RXH2 1/20 0.46
LSS P48449 2/20 0.46
HTT P42858 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2030465 0.84 IDO1 (0.50) RAB9ANPC1LMNAMEN1KMT2A
SCHEMBL13652636 0.83 ALDH1A1 (0.54) RAB9ANPC1LMNAMAPTMEN1
SCHEMBL8011467 0.82 MEN1 (0.54) RAB9ANPC1LMNAMAPTMEN1
SCHEMBL8005599 0.81 LMNA (0.67) RAB9ANPC1LMNAMAPTMEN1
SCHEMBL8007503 0.81 SRD5A2 (0.52) RAB9ANPC1LMNAMAPTMEN1
SCHEMBL8007967 0.81 MAPT (0.47) RAB9ANPC1LMNAMAPTMEN1
SCHEMBL28400194 0.79 HTT (0.67) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL23616789 0.77 MAPT (0.44) RAB9ANPC1LMNAMAPTMEN1
SCHEMBL132367 0.77 LMNA (0.73) RAB9ALMNAMAPTMEN1KMT2A
SCHEMBL3842531 0.77 LMNA (0.73) RAB9ALMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6077866-A EXHIBIT POWERFUL INSECTICIDAL ACTION, ESPECIALLY AGAINST LEPIDOPTERA, COLEOPTERA AND SOIL INSECTS NIHON BAYER AGROCHEM K.K. (JP) 2000-06-20 US disclosed
EP-0742202-B1 Benzophenone hydrazone derivatives as insecticides BAYER AGROCHEM KK (JP) 1999-12-01 EP disclosed
EP-0742202-A2 Benzophenone hydrazone derivatives as insecticides NIHON BAYER AGROCHEM K.K. (JP) 1996-11-13 EP disclosed