Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776074 | 0.84 | LMNA (0.58) | LMNANPC1RAB9AALDH1A1IDO1 | |
| SCHEMBL13652636 | 0.83 | ALDH1A1 (0.54) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7995420 | 0.82 | LMNA (0.48) | LMNALTA4HMAPTS1PR1SMN1; SMN2 | |
| SCHEMBL8007967 | 0.81 | MAPT (0.47) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL7995645 | 0.81 | RAB9A (0.57) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8007503 | 0.81 | SRD5A2 (0.52) | LMNAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL20157757 | 0.80 | LMNA (0.50) | LMNAMAPTS1PR1SMN1; SMN2NPC1 | |
| SCHEMBL3406790 | 0.79 | LMNA (0.65) | LMNALTA4HMAPTS1PR1SMN1; SMN2 | |
| SCHEMBL8577031 | 0.78 | LTA4H (0.57) | LMNALTA4HMAPTS1PR1SMN1; SMN2 | |
| SCHEMBL9018906 | 0.78 | LTA4H (0.57) | LMNALTA4HMAPTS1PR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077866-A | EXHIBIT POWERFUL INSECTICIDAL ACTION, ESPECIALLY AGAINST LEPIDOPTERA, COLEOPTERA AND SOIL INSECTS | NIHON BAYER AGROCHEM K.K. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0742202-B1 | Benzophenone hydrazone derivatives as insecticides | BAYER AGROCHEM KK (JP) | 1999-12-01 | — | — | EP | disclosed |
| EP-0742202-A2 | Benzophenone hydrazone derivatives as insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-11-13 | — | — | EP | disclosed |