Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514628 | 0.84 | APP (0.47) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13652636 | 0.83 | ALDH1A1 (0.54) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7995645 | 0.81 | RAB9A (0.57) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8005599 | 0.81 | LMNA (0.67) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8007503 | 0.81 | SRD5A2 (0.52) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL23616789 | 0.77 | MAPT (0.44) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9389844 | 0.77 | TPMT (0.65) | MAPTSMN1; SMN2LMNATPMTCA1 | |
| SCHEMBL1244094 | 0.77 | TPMT (0.65) | MAPTSMN1; SMN2LMNATPMTCA1 | |
| SCHEMBL3841301 | 0.77 | TPMT (0.65) | MAPTSMN1; SMN2LMNATPMTCA1 | |
| SCHEMBL8665833 | 0.76 | ALDH1A1 (0.59) | MAPTNPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077866-A | EXHIBIT POWERFUL INSECTICIDAL ACTION, ESPECIALLY AGAINST LEPIDOPTERA, COLEOPTERA AND SOIL INSECTS | NIHON BAYER AGROCHEM K.K. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0742202-B1 | Benzophenone hydrazone derivatives as insecticides | BAYER AGROCHEM KK (JP) | 1999-12-01 | — | — | EP | disclosed |
| EP-0742202-A2 | Benzophenone hydrazone derivatives as insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-11-13 | — | — | EP | disclosed |