Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001578 | 1.00 | HTR2A (0.57) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7997990 | 1.00 | HTR2A (0.57) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7998303 | 0.90 | HTR1D (0.47) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7984083 | 0.81 | HTR2B (0.52) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7983652 | 0.79 | SLC6A4 (0.41) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL10491412 | 0.78 | MEN1 (0.75) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL23927859 | 0.78 | HTR6 (0.52) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL7993961 | 0.77 | HTR2A (0.53) | HTR2AMTNR1AMTNR1BHTR6HTR1A | |
| SCHEMBL7997830 | 0.77 | HTR2A (0.53) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL8001659 | 0.77 | MPO (0.62) | HTR2AKMT2AMTNR1AMTNR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |