Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673329 | 0.98 | FFAR4 (0.61) | FFAR4FFAR1L3MBTL1APPMEN1 | |
| SCHEMBL3690496 | 0.93 | CALM1 (0.60) | FFAR4FFAR1APPMEN1KMT2A | |
| SCHEMBL2840795 | 0.91 | FFAR4 (0.55) | FFAR4FFAR1L3MBTL1APPMEN1 | |
| SCHEMBL28323456 | 0.90 | L3MBTL1 (0.54) | FFAR4FFAR1L3MBTL1APPMEN1 | |
| SCHEMBL347209 | 0.88 | FFAR4 (0.61) | FFAR4FFAR1MEN1KMT2APLA2G4A | |
| SCHEMBL8501979 | 0.87 | MAPK1 (0.54) | L3MBTL1APPMEN1KMT2ACALM1 | |
| SCHEMBL5607847 | 0.87 | CALM1 (0.56) | L3MBTL1APPCALM1HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL3225386 | 0.86 | FFAR4 (0.59) | FFAR4FFAR1MEN1KMT2APLA2G4A | |
| SCHEMBL21494459 | 0.85 | PDE4D (0.59) | L3MBTL1MEN1KMT2ACALM1HDAC1 | |
| SCHEMBL7995937 | 0.84 | L3MBTL1 (0.51) | FFAR4FFAR1L3MBTL1APPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075041-A | TUMOR NECROSIS FACTOR | CELGENE CORPORATION (US) | 2000-06-13 | — | — | US | disclosed |