Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009492 | 0.93 | TP53 (0.55) | PTGS1PTGS2CCNA2CDK2KDM4E | |
| SCHEMBL11248919 | 0.84 | PTGDR2 (0.50) | PTGS1PTGS2CCNA2CDK2RAB9A | |
| SCHEMBL5217314 | 0.83 | ESR1 (0.68) | PTGS1PTGS2RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL11245609 | 0.81 | ALDH1A1 (0.48) | CCNA2CDK2KDM4EHTTALDH1A1 | |
| SCHEMBL23403668 | 0.80 | RPA1 (0.47) | RAB9AKDM4ESMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11251973 | 0.80 | RPA1 (0.50) | PTGS2CCNA2CDK2RAB9AKDM4E | |
| SCHEMBL5218437 | 0.79 | CDK2 (0.45) | PTGS1PTGS2CCNA2CDK2RAB9A | |
| SCHEMBL8008424 | 0.79 | L3MBTL1 (0.52) | RAB9AKDM4ESMN1; SMN2HTTALDH1A1 | |
| SCHEMBL21121386 | 0.78 | ESR1 (0.64) | KDM4EALDH1A1MAPTTP53ESR1 | |
| SCHEMBL11733429 | 0.77 | PTGS2 (0.51) | PTGS1PTGS2CCNA2CDK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000019994-A9 | ESTROGEN RECEPTOR LIGANDS | UNIV ILLINOIS (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000019994-A1 | ESTROGEN RECEPTOR LIGANDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-13 | — | — | WO | disclosed |