Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995971 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TDP1L3MBTL1ARCYP19A1 | |
| SCHEMBL7996739 | 0.82 | POLB (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL19457046 | 0.81 | ALDH1A1 (0.61) | ALDH1A1TDP1L3MBTL1ARCYP19A1 | |
| SCHEMBL7999903 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TDP1L3MBTL1ARCYP19A1 | |
| SCHEMBL27168526 | 0.79 | HSP90AA1 (0.47) | ALDH1A1TDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL15018444 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TDP1L3MBTL1ARCYP19A1 | |
| SCHEMBL29394371 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TDP1L3MBTL1ARCYP19A1 | |
| SCHEMBL22589779 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TDP1L3MBTL1ARCYP19A1 | |
| SCHEMBL11297088 | 0.73 | TDP1 (0.54) | ALDH1A1TDP1L3MBTL1RAB9ANPC1 | |
| SCHEMBL1126722 | 0.73 | ALDH1A1 (0.62) | ALDH1A1TDP1L3MBTL1ARRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001044185-A1 | CARBON MONOXIDE-BASED SYNTHESIS OF SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |