Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MDH1 | P40925 | 3/20 | 0.47 |
| ▸ | MDH2 | P40926 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957573 | 0.82 | KMT2A (0.56) | KMT2AMEN1L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL12199660 | 0.81 | ALDH1A1 (0.52) | KMT2AALDH1A1NPSR1GAACYP1A2 | |
| SCHEMBL14354628 | 0.80 | GAA (0.61) | KMT2AMEN1GAAMAPK1MAPT | |
| SCHEMBL5736625 | 0.79 | SMN1; SMN2 (0.50) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL2856689 | 0.78 | LMNA (0.55) | KMT2AMEN1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7256606 | 0.78 | KMT2A (0.50) | KMT2AMEN1L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL10887938 | 0.77 | CA1 (0.65) | GAAMAPTRAB9AHIF1A | |
| SCHEMBL12125403 | 0.76 | L3MBTL1 (0.65) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL7308049 | 0.76 | TSHR (0.51) | KMT2AMEN1L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL14930228 | 0.75 | KMT2A (0.55) | KMT2AMEN1L3MBTL1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |