Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | PHPT1 | Q9NRX4 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13608498 | 0.87 | POLB (0.56) | LMNAHTTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL30567224 | 0.86 | MAPT (0.62) | LMNAHTTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL2855386 | 0.86 | MAPT (0.62) | LMNAHTTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL7256606 | 0.86 | KMT2A (0.50) | KDM4ESMN1; SMN2POLBHDAC1MTNR1A | |
| SCHEMBL27451728 | 0.84 | KDM4E (0.54) | LMNAKDM4ESMN1; SMN2POLBHDAC1 | |
| SCHEMBL359701 | 0.82 | MAPT (0.56) | LMNAHTTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL2502603 | 0.82 | MAPT (0.71) | HTTTSHRKDM4ESMN1; SMN2POLB | |
| SCHEMBL1391102 | 0.82 | MEN1 (0.50) | HTTSMN1; SMN2HDAC1MTNR1AMTNR1B | |
| SCHEMBL11051072 | 0.81 | POLB (0.50) | LMNAHTTTSHRKDM4ESMN1; SMN2 | |
| SCHEMBL2847925 | 0.81 | ALDH1A1 (0.64) | LMNAHTTTSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070016-A1 | Method and composition for increasing reproduction in mammalian and avian species | THE UNIVERSITY OF UTAH (US) | 1983-01-19 | — | — | EP | claimed |
| US-7794761-B2 | Methods for inducing anti-anxiety and calming effects in animals and humans | SEROCTIN RESEARCH & TECHNOLOGY, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-7794761-B2 | Methods for inducing anti-anxiety and calming effects in animals and humans | SEROCTIN RESEARCH & TECHNOLOGY, INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-7521468-B2 | Compounds for use in weight loss and appetite suppression in humans | SEROCTIN RESEARCH & TECHNOLOGY, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-7521468-B2 | Compounds for use in weight loss and appetite suppression in humans | SEROCTIN RESEARCH & TECHNOLOGY, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| EP-1765338-A1 | METHODS FOR INDUCING ANTI-ANXIETY AND CALMING EFFECTS IN ANIMALS AND HUMANS | Seroctin Research & Technologies, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20060223796-A1 | Novel compounds for use in weight loss and appetite suppression in humans | SAVANNA HEALTH LLC | 2006-10-05 | — | — | US | disclosed |
| WO-2006017281-A1 | METHODS FOR INDUCING ANTI-ANXIETY AND CALMING EFFECTS IN ANIMALS AND HUMANS | SEROCTIN RESEARCH & TECHNOLOGY, INC. (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20050250772-A1 | Methods for inducing anti-anxiety and calming effects in animals and humans | SAVANNA HEALTH LLC | 2005-11-10 | — | — | US | disclosed |
| US-20040209877-A1 | Methods for augmenting immune defenses contemplating the administration of phenolic and indoleamine-like compounds for use in animals ans humans | SEROCTIN RESEARCH & TECHNOLOGY, INC. | 2004-10-21 | — | — | US | disclosed |
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0343574-A1 | 4(1H)-quinolone derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |
| EP-0070016-A1 | Method and composition for increasing reproduction in mammalian and avian species | THE UNIVERSITY OF UTAH (US) | 1983-01-19 | — | — | EP | disclosed |
| EP-0006220-B1 | PROCESS FOR THE PREPARATION OF 3-ACYL-2-ALKYL(ARYL)-1.3.2-BENZOXAZAPHOSPHOLANES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-19 | — | — | EP | disclosed |
| EP-0006195-B1 | PROCESS FOR PREPARING DELTA-3 1-OXOPHOSPHOLENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-05-13 | — | — | EP | disclosed |
| US-4263231-A | REACTING DICHLOROPHOSPHANES AND 2-N-ACYLAMINOPHENOLS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-04-21 | — | — | US | disclosed |
| US-4247488-A | Process for the preparation of 1-oxophosphol-Δ3 -enes | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-27 | — | — | US | disclosed |
| EP-0006220-A1 | Process for the preparation of 3-Acyl-2-alkyl(aryl)-1.3.2-benzoxazaphospholanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-09 | — | — | EP | disclosed |
| EP-0006195-A1 | Process for preparing delta-3 1-oxophospholenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209877-A1 | Methods for augmenting immune defenses contemplating the administration of phenolic and indoleamine-like compounds for use in animals ans humans | HAAO, HMOX1, IDO1 | LMNA 1850/4885HTT 1548/4885TSHR 3911/4885 |
| US-20050250772-A1 | Methods for inducing anti-anxiety and calming effects in animals and humans | CALM1, HAAO, MYB | LMNA 820/4885HTT 1003/4885TSHR 4265/4885 |
| US-20060223796-A1 | Novel compounds for use in weight loss and appetite suppression in humans | CPT1B, EGLN3, MYB | LMNA 2189/4885HTT 1076/4885TSHR 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.