Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24590196 | 0.73 | CYP1A1 (0.64) | CSNK2A1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL24263371 | 0.73 | NPC1 (0.65) | CSNK2A1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL17188760 | 0.72 | UCHL1 (0.46) | MAPTMEN1KMT2AMAPK1KDM4E | |
| SCHEMBL1821135 | 0.72 | KMT2A (0.69) | CSNK2A1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL11139020 | 0.71 | CSNK2A1 (0.66) | CSNK2A1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL17188766 | 0.71 | KMT2A (0.57) | NPC1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12302712 | 0.71 | MEN1 (0.67) | CSNK2A1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL12297227 | 0.70 | CSNK2A1 (0.70) | CSNK2A1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL7997391 | 0.70 | KCNQ1 (0.53) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL7997071 | 0.69 | NPC1 (0.52) | CSNK2A1RAB9ANPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129109-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-22 | — | — | WO | disclosed |