Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 17/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997071 | 0.90 | NPC1 (0.52) | KCNQ1SMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL7997452 | 0.90 | TRPV1 (0.47) | KCNQ1SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL7987507 | 0.89 | CNR2 (0.47) | KCNQ1SMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL17188760 | 0.85 | UCHL1 (0.46) | KCNQ1MEN1MAPTKMT2AMAPK1 | |
| SCHEMBL17188767 | 0.83 | RAB9A (0.51) | SMN1; SMN2LMNAMEN1MAPTHTT | |
| SCHEMBL7999807 | 0.73 | CNR2 (0.44) | KCNQ1SMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL7943694 | 0.71 | ELANE (0.46) | RAB9AALDH1A1 | |
| SCHEMBL7996009 | 0.70 | CSNK2A1 (0.52) | SMN1; SMN2LMNAMEN1MAPTHTT | |
| SCHEMBL12780144 | 0.69 | ELANE (0.46) | — | |
| SCHEMBL7942699 | 0.69 | THRB (0.46) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129109-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-22 | — | — | WO | disclosed |