Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.42 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 3/20 | 0.41 |
| ▸ | ATP4B | P51164 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987507 | 0.86 | CNR2 (0.47) | PIK3CAPIK3CDKDM4EMAPTKCNQ1 | |
| SCHEMBL7997391 | 0.85 | KCNQ1 (0.53) | MAPTMAPK1KCNQ1MEN1KMT2A | |
| SCHEMBL7997071 | 0.84 | NPC1 (0.52) | UCHL1USP30KDM4EMAPTMAPK1 | |
| SCHEMBL7997452 | 0.83 | TRPV1 (0.47) | PIK3CAPIK3CDKCNQ1PIK3C2BPIK3CB | |
| SCHEMBL12780144 | 0.78 | ELANE (0.46) | HTR1AHTR7ELANE | |
| SCHEMBL17188767 | 0.77 | RAB9A (0.51) | KDM4EMAPTMEN1KMT2A | |
| SCHEMBL12336180 | 0.75 | ELANE (0.46) | HTR1AHTR7MEN1KMT2AELANE | |
| SCHEMBL7943694 | 0.74 | ELANE (0.46) | ELANE | |
| SCHEMBL7996009 | 0.72 | CSNK2A1 (0.52) | KDM4EMAPTMAPK1MEN1KMT2A | |
| SCHEMBL17188722 | 0.72 | CCNT1 (0.51) | PIK3CAPIK3CDKCNQ1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265606-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |