Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978699 | 0.80 | MAPT (0.52) | HTTKDM4EKMT2ALMNAMEN1 | |
| SCHEMBL7978522 | 0.77 | — | — | |
| SCHEMBL5386406 | 0.77 | HSD17B10 (0.45) | KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7447432 | 0.76 | HSD17B10 (0.47) | KDM4EKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7990353 | 0.75 | KDM4E (0.52) | HTTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5381026 | 0.74 | AR (0.44) | HTTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL7956433 | 0.73 | MAPT (0.64) | SMOHTTL3MBTL1KDM4EKMT2A | |
| SCHEMBL4105526 | 0.72 | DGAT1 (0.62) | PARP1 | |
| SCHEMBL7978276 | 0.70 | HRH4 (0.49) | — | |
| SCHEMBL28033559 | 0.70 | PARP1 (0.63) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070728-A1 | 2-[NITROGEN-HETEROCYCLIC]PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | claimed |