Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.49 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998204 | 0.81 | GRM2 (0.41) | ALDH1A1TSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL8001769 | 0.80 | GRM2 (0.38) | ALDH1A1TSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL7997626 | 0.78 | LMNA (0.39) | ALDH1A1TSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL7998049 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL7994931 | 0.77 | HTR7 (0.34) | ALDH1A1TSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL7994276 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHRSMN1; SMN2LMNAHPGD | |
| SCHEMBL7996539 | 0.75 | TP53 (0.41) | ALDH1A1SMN1; SMN2LMNATP53THRB | |
| SCHEMBL7997836 | 0.75 | TP53 (0.41) | ALDH1A1SMN1; SMN2LMNATP53THRB | |
| SCHEMBL7994234 | 0.74 | TP53 (0.40) | ALDH1A1SMN1; SMN2LMNATP53THRB | |
| SCHEMBL7995736 | 0.73 | CYP1A2 (0.43) | ALDH1A1SMN1; SMN2LMNATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |