Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.38 |
| ▸ | CA2 | P00918 | 11/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075495 | 0.81 | ALDH1A1 (0.45) | CA1CA2CA9KDM4EMEN1 | |
| SCHEMBL3258334 | 0.79 | CA2 (0.50) | CA1CA2CA9KDM4EPPARG | |
| SCHEMBL8000512 | 0.76 | CYP4A11 (0.44) | CA1CA2CA9PPARACA4 | |
| SCHEMBL13067604 | 0.74 | CA1 (0.50) | CA1CA2CA9KDM4EKMT2A | |
| SCHEMBL1246773 | 0.74 | CA2 (0.48) | CA1CA2CA9KDM4EPPARA | |
| SCHEMBL28890376 | 0.73 | CA2 (0.41) | CA1CA2CA9KDM4ENPC1 | |
| SCHEMBL3142520 | 0.73 | KMT2A (0.51) | CA1CA2CA9NPC1RAB9A | |
| SCHEMBL11039771 | 0.73 | KMT2A (0.50) | CA1CA2CA9RAB9AKMT2A | |
| SCHEMBL6991225 | 0.72 | CA1 (0.48) | CA1CA2CA9KDM4ENPC1 | |
| SCHEMBL13527822 | 0.72 | CA2 (0.50) | CA1CA2CA9KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |