Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14053392 | 0.85 | CYP4A11 (0.47) | CYP4A11CYP4F2CA2CA1CA12 | |
| SCHEMBL16246248 | 0.83 | CYP4F2 (0.46) | CYP4A11CYP4F2CA2CA1CA12 | |
| SCHEMBL5171523 | 0.81 | CNR1 (0.39) | CYP4A11CYP4F2CA2CA1ALOX15 | |
| SCHEMBL27321565 | 0.81 | LOXL2 (0.44) | HRH3 | |
| SCHEMBL27551940 | 0.79 | SMN1; SMN2 (0.36) | TSHRTDP1ALOX15HRH3 | |
| SCHEMBL8866817 | 0.76 | CYP4F2 (0.57) | CYP4A11CYP4F2CA2PPARATSHR | |
| SCHEMBL7996874 | 0.76 | CA1 (0.38) | CA2CA1CA12CA4CA9 | |
| SCHEMBL66152 | 0.76 | ALDH1A1 (0.58) | CYP4A11CYP4F2CA2TSHRTDP1 | |
| SCHEMBL13734403 | 0.74 | ALDH1A1 (0.52) | TSHRTDP1ALOX15 | |
| SCHEMBL16937417 | 0.74 | ALDH1A1 (0.50) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |
| EP-0991632-A1 | NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES | Astra Aktiebolag (SE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057941-A1 | NEW THIAZOLIDINEDIONE, OXAZOLIDINEDIONE AND OXADIAZOLIDINEDIONE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1998-12-23 | — | — | WO | disclosed |