Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.56 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13099833 | 0.89 | KDM4E (0.65) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL30581469 | 0.89 | KDM4E (0.65) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL216351 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL1706850 | 0.87 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL5799758 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL3598134 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL17847080 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL30072726 | 0.84 | TDP1 (0.60) | ALDH1A1MAPTSMN1; SMN2LMNARAB9A | |
| SCHEMBL1141627 | 0.84 | TDP1 (0.60) | ALDH1A1MAPTSMN1; SMN2LMNARAB9A | |
| SCHEMBL11241296 | 0.80 | RAB9A (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001044185-A1 | CARBON MONOXIDE-BASED SYNTHESIS OF SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |