Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598134 | 0.92 | ALDH1A1 (0.50) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16792371 | 0.85 | NLRP3 (0.48) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16792345 | 0.85 | PTPN7 (0.53) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16861184 | 0.84 | GPR35 (0.51) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14252839 | 0.84 | CA12 (0.55) | KDM4EALDH1A1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL29860136 | 0.82 | ALDH1A1 (0.43) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL13099833 | 0.82 | KDM4E (0.65) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30581469 | 0.82 | KDM4E (0.65) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7996901 | 0.80 | ALDH1A1 (0.56) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11245888 | 0.79 | RAB9A (0.54) | RAB9AKDM4EALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310527-A | DISORDERS OF CAROIAC RHYTHM AND CORONARY HEART DISEASES AND HYDPERTENSION | CIBA-GEIGY CORPORATION (US) | 1982-01-12 | — | — | US | disclosed |
| US-4140789-A | ADRENERGIC BLOCKING AGENTS, CARDIOTONIC, ANTIARRHYTHMIA, HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |