Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.65 |
| ▸ | MMP1 | P03956 | 6/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | GRK2 | P25098 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689527 | 0.81 | MMP1 (0.83) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL7324083 | 0.79 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL6388043 | 0.77 | HDAC2 (0.65) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL1941210 | 0.77 | CA2 (0.67) | MMP1CTDSP1POLBKMT2ATDP1 | |
| SCHEMBL6387224 | 0.76 | HDAC1 (0.68) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL947975 | 0.75 | HSD11B1 (0.63) | CTDSP1POLBKMT2ATDP1GRK2 | |
| SCHEMBL21149882 | 0.75 | HDAC1 (0.71) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL7012692 | 0.75 | KMT2A (0.52) | CTDSP1POLBKMT2ATDP1GRK2 | |
| SCHEMBL5387555 | 0.74 | PLCG1 (0.59) | CTDSP1POLBKMT2ATDP1GRK2 | |
| SCHEMBL28446468 | 0.74 | HDAC1 (0.72) | HDAC1HDAC8HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288086-B1 | COMPOUNDS SUCH AS 1-METHYL-4-(4-BUTOXY-BENZENESULFONYL) -PIPERIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE USED TO TREAT ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, ETC.; LOW MOLECULAR WEIGHT AND NON-PEPTIDAL | AMERICAN CYANAMID COMPANY | 2001-09-11 | — | — | US | disclosed |