Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 11/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.65 |
| ▸ | MMP1 | P03956 | 5/20 | 0.63 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6387224 | 0.99 | HDAC1 (0.68) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6386202 | 0.80 | MEP1B (0.67) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL7324083 | 0.79 | HDAC1 (1.00) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6384827 | 0.79 | MEP1B (0.70) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6386199 | 0.78 | HDAC1 (0.88) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL10583534 | 0.77 | HDAC1 (0.53) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL7996970 | 0.77 | HDAC1 (0.65) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL10580753 | 0.77 | HDAC1 (0.53) | HDAC2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL7010857 | 0.75 | HSD11B1 (0.58) | MMP1KMT2AMEN1MMP2MMP7 | |
| SCHEMBL8290529 | 0.75 | ALDH1A1 (0.72) | MMP1MEP1BKMT2AMEN1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119305-A1 | Il-6 production inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-02 | — | — | US | claimed |
| US-20050119305-A1 | Il-6 production inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119305-A1 | Il-6 production inhibitors | IL6, IL6ST, PADI6 | HDAC2 2783/4885HDAC1 1343/4885HDAC3 1988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.