Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19171684 | 0.75 | CA1 (0.39) | — | |
| SCHEMBL23194332 | 0.75 | LMNA (0.34) | — | |
| SCHEMBL564823 | 0.69 | — | — | |
| SCHEMBL7995257 | 0.67 | SMN1; SMN2 (0.51) | — | |
| SCHEMBL15128666 | 0.64 | METAP1 (0.39) | CYP1A2CYP2A6METAP1PARP10PARP11 | |
| SCHEMBL30743772 | 0.64 | IKBKB (0.41) | CYP1A2CYP2A6METAP1PARP10PARP11 | |
| SCHEMBL3896106 | 0.64 | IKBKB (0.41) | CYP1A2CYP2A6METAP1PARP10PARP11 | |
| SCHEMBL19986498 | 0.63 | LMNA (0.34) | — | |
| SCHEMBL10268406 | 0.63 | ACHE (0.42) | — | |
| SCHEMBL402517 | 0.62 | METAP1 (0.42) | CYP1A2CYP2A6METAP1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3949969-A2 | BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF | Silverback Therapeutics, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |