Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892013 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28891930 | 0.70 | ALDH1A1 (0.31) | ALDH1A1HTTNPSR1TAAR1 | |
| SCHEMBL299428 | 0.70 | ALDH1A1 (0.38) | SIGMAR1ALDH1A1HTTNPSR1MAOA | |
| SCHEMBL16667155 | 0.67 | MAOA (0.42) | SIGMAR1ALDH1A1HTTNPSR1MAOA | |
| SCHEMBL25217435 | 0.67 | ALDH1A1 (0.36) | SIGMAR1ALDH1A1HTTNPSR1MAOA | |
| SCHEMBL28761978 | 0.67 | ALDH1A1 (0.34) | SIGMAR1ALDH1A1HTTNPSR1MAOA | |
| SCHEMBL5176382 | 0.67 | SIGMAR1 (0.35) | SIGMAR1ALDH1A1HTTNPSR1MAOA | |
| SCHEMBL17296059 | 0.67 | ALDH1A1 (0.34) | SIGMAR1ALDH1A1HTTNPSR1MAOA | |
| Lithium Ion SCHEMBL28422154 | 0.65 | KIF11 (0.32) | — | |
| SCHEMBL25222150 | 0.65 | ALDH1A1 (0.35) | SIGMAR1ALDH1A1HTTNPSR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023298-A1 | BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF | Phillips Petroleum Company (US) | 2000-08-02 | — | — | EP | disclosed |
| EP-1023298-A4 | BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF | PHILLIPS PETROLEUM CO (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999014219-A1 | BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF | PHILLIPS PETROLEUM COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |