Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001769 | 0.87 | GRM2 (0.38) | LMNAHTTMAPTKMT2AALDH1A1 | |
| SCHEMBL7998204 | 0.83 | GRM2 (0.41) | LMNAHTTMAPTKMT2AALDH1A1 | |
| SCHEMBL7998049 | 0.82 | ALDH1A1 (0.38) | LMNAMAPTKMT2AALDH1A1MAPK1 | |
| SCHEMBL7994931 | 0.82 | HTR7 (0.34) | LMNAHTTMAPTKMT2AALDH1A1 | |
| SCHEMBL7994276 | 0.79 | ALDH1A1 (0.36) | LMNAHTTMAPTKMT2AALDH1A1 | |
| SCHEMBL8002275 | 0.78 | ALDH1A1 (0.49) | LMNAMAPTALDH1A1MAPK1HPGD | |
| SCHEMBL7994293 | 0.71 | NPC1 (0.42) | LMNAHTTMAPTKMT2AALDH1A1 | |
| SCHEMBL7994182 | 0.71 | KMT2A (0.40) | LMNAHTTMAPTKMT2AALDH1A1 | |
| SCHEMBL8001947 | 0.70 | GFER (0.39) | LMNAKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7995706 | 0.69 | HSP90AA1 (0.41) | LMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |