Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996082 | 0.89 | GPR119 (0.42) | F10PRSS1GPR119 | |
| SCHEMBL7999734 | 0.83 | F10 (0.39) | F10PRSS1GPR119 | |
| SCHEMBL7996365 | 0.81 | PLA2G2A (0.39) | OPRM1OPRK1 | |
| SCHEMBL7986762 | 0.80 | F10 (0.55) | F10PRSS1 | |
| SCHEMBL7999835 | 0.79 | F10 (0.58) | F10PRSS1 | |
| SCHEMBL7986780 | 0.78 | F10 (0.62) | F10PRSS1 | |
| SCHEMBL7986772 | 0.73 | F10 (0.57) | F10PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7997619 | 0.73 | PRSS1 (0.52) | F10PRSS1 | |
| SCHEMBL7986943 | 0.73 | F10 (0.56) | F10PRSS1 | |
| SCHEMBL7986749 | 0.73 | F10 (0.56) | F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |