Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.39 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996082 | 0.92 | GPR119 (0.42) | F10CYP46A1HRH3PRSS1GPR119 | |
| Trifluoroacetic Acid SCHEMBL7997792 | 0.85 | PRSS1 (0.52) | F10PRSS1F2 | |
| SCHEMBL7997696 | 0.83 | F10 (0.44) | F10PRSS1GPR119 | |
| SCHEMBL7999919 | 0.81 | CYP46A1 (0.39) | CYP46A1HRH3 | |
| Trifluoroacetic Acid SCHEMBL7997619 | 0.77 | PRSS1 (0.52) | F10PRSS1F2 | |
| SCHEMBL7999929 | 0.76 | HRH3 (0.52) | F10CYP46A1HRH3PRSS1F2 | |
| SCHEMBL7996357 | 0.75 | NPC1 (0.54) | F10HRH3PRSS1PLGF2 | |
| SCHEMBL7987038 | 0.73 | F10 (0.54) | F10CYP46A1HRH3PRSS1PLG | |
| SCHEMBL7997768 | 0.70 | NPC1 (0.49) | F10HRH3PRSS1PLGF2 | |
| SCHEMBL7986949 | 0.67 | F10 (0.58) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |