Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315359 | 0.80 | ROCK2 (0.35) | KMT2ALMNAMEN1ALDH1A1TSHR | |
| SCHEMBL12128642 | 0.79 | TRIM24 (0.39) | KMT2ALMNAMEN1TDP1SRC | |
| SCHEMBL1314189 | 0.78 | ROCK2 (0.33) | ALDH1A1HSD17B10GAAKDM4E | |
| Formaldehyde SCHEMBL17583570 | 0.77 | ROCK2 (0.32) | KMT2AMEN1ALDH1A1HPGDHTT | |
| SCHEMBL17583591 | 0.77 | ROCK2 (0.33) | MAPTGAAKDM4E | |
| SCHEMBL520084 | 0.75 | BCHE (0.37) | KMT2ALMNAMEN1ALDH1A1TSHR | |
| SCHEMBL8106088 | 0.74 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL19591133 | 0.74 | ROCK2 (0.31) | — | |
| SCHEMBL8091041 | 0.73 | — | — | |
| SCHEMBL14905782 | 0.72 | GAA (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114080379-B | Hydrogenation of esters to alcohols in the presence of Ru-PNN complexes | 巴斯夫欧洲公司 | 2024-02-23 | — | — | CN | disclosed |
| US-11708316-B2 | Hydrogenation of esters to alcohols in the presence of a Ru-PNN complex | BASF SE (DE) | 2023-07-25 | — | — | US | disclosed |
| CN-114080379-A | Hydrogenation of esters to alcohols in the presence of Ru-PNN complexes | 巴斯夫欧洲公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-112375100-B | Chiral phosphine nitrogen phosphine tridentate ligand, preparation method and application thereof | 珠海复旦创新研究院 | 2021-12-21 | — | — | CN | disclosed |
| CN-112375100-A | Chiral phosphine nitrogen phosphine tridentate ligand, preparation method and application thereof | 珠海复旦创新研究院 | 2021-02-19 | — | — | CN | disclosed |
| US-6124476-A | SUZUKI CROSS-COUPLING REACTIONS. PHOSPHINOBENZALDEHYDES AND ACETALS | SYMYX TECHNOLOGIES, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| WO-2000008032-A1 | CATALYST LIGANDS USEFUL FOR CROSS-COUPLING REACTIONS | SYMYX TECHNOLOGIES, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708316-B2 | Hydrogenation of esters to alcohols in the presence of a Ru-PNN complex | ADH1A, PNN, ADH1C | KMT2A 771/4885LMNA 214/4885MEN1 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.