Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28796978 | 0.87 | HPRT1 (0.56) | CTSBALDH1A1CASP6HPRT1CYP3A4 | |
| SCHEMBL2165535 | 0.84 | HPRT1 (0.49) | CTSBALDH1A1CASP6HPRT1HSD17B10 | |
| SCHEMBL28772861 | 0.84 | CTSB (0.59) | CTSBALDH1A1CASP6CYP3A4ALOX15 | |
| SCHEMBL30739459 | 0.84 | CTSB (0.59) | CTSBALDH1A1CASP6CYP3A4ALOX15 | |
| SCHEMBL4539666 | 0.84 | CTSB (0.59) | CTSBALDH1A1CASP6CYP3A4ALOX15 | |
| 1-Nitropyrene SCHEMBL29450697 | 0.84 | ALDH1A1 (0.57) | CTSBALDH1A1HPRT1CYP3A4ALOX15 | |
| 1-Nitropyrene SCHEMBL339725 | 0.84 | ALDH1A1 (0.57) | CTSBALDH1A1HPRT1CYP3A4ALOX15 | |
| 1-Nitropyrene SCHEMBL28624685 | 0.82 | ALDH1A1 (0.52) | CTSBALDH1A1CASP6HPRT1CYP3A4 | |
| 1-Nitropyrene SCHEMBL28378090 | 0.82 | ALDH1A1 (0.55) | CTSBALDH1A1HPRT1CYP3A4ALOX15 | |
| SCHEMBL12014664 | 0.81 | CYP1A2 (0.61) | CTSBALDH1A1CASP6HPRT1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294380-B1 | Liver cell clones for use in extracorporeal liver-assist device | JMS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1063289-A1 | Liver cell clones for artifical liver and extracorporeal liver assist device | JMS Co., Ltd. (JP) | 2000-12-27 | — | — | EP | disclosed |