Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12595649 | 1.00 | CA12 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL18431558 | 1.00 | CA12 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL12595648 | 1.00 | CA12 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL17918952 | 0.79 | ALDH1A1 (0.31) | — | |
| SCHEMBL25098697 | 0.79 | ALDH1A1 (0.31) | — | |
| SCHEMBL25808461 | 0.79 | PIK3C3 (0.33) | — | |
| SCHEMBL17404005 | 0.76 | EBP (0.30) | — | |
| SCHEMBL1259404 | 0.76 | CA12 (0.32) | CA12CA1CA2CA9 | |
| SCHEMBL5365309 | 0.76 | — | — | |
| SCHEMBL1259402 | 0.76 | NSD2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144829-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2022-05-12 | — | — | US | disclosed |
| WO-2022087634-A1 | CTPS1 INHIBITORS AND USES THEREOF | NIMBUS CLOTHO, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| US-11180494-B2 | Substituted amino acids as integrin inhibitors | PLIANT THERAPEUTICS, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20210145812-A1 | AMINOAMIDE COMPOUNDS | BIOTHERYX, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-20200109141-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2020-04-09 | — | — | US | disclosed |
| US-6054033-A | AMINE-MODIFIED POLYPHENOL EPOXY RESIN, AN ACRYLIC COPOLYMER HAVING IONIZABLE GROUPS, AND RESIN PARTICLES COMPRISED OF A CORE OF GELLED HYDROPHOBIC RESIN AND A SHELL LAYER OF AMINO GROUP-CONTAINING HYDROPHILIC RESIN. | NIPPON PAINT CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0448341-B1 | Coating composition for precoated metal material | NIPPON PAINT CO LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| EP-0448341-A1 | Coating composition for precoated metal material | NIPPON PAINT CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |
| US-4659781-A | Reactive acrylic oligomer, grafted acrylic resinous composition based on said oligomer and coating composition containing the same | NIPPON PAINT CO., LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| US-3970608-A | Epoxidized acetylene-conjugated diene random copolymer and the curable composition comprising the same | BRIDGESTONE TIRE COMPANY LIMITED (JA) | 1976-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144829-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | ITGB6, ITGA1, ITGAL | CA12 2474/4885CA1 3778/4885CA2 3741/4885 |
| US-20200109141-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | ITGB6, ITGA1, ITGAL | CA12 2474/4885CA1 3778/4885CA2 3741/4885 |
| US-11180494-B2 | Substituted amino acids as integrin inhibitors | ITGB6, ITGA1, ITGB1 | CA12 3861/4885CA1 4552/4885CA2 4386/4885 |
| US-20210145812-A1 | AMINOAMIDE COMPOUNDS | DNPEP, BCAT2, AADAT | CA12 2964/4885CA1 1892/4885CA2 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.