Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019091 | 0.93 | KDM4E (0.37) | HSD11B1KDM4EUSP2KMT2ACA12 | |
| SCHEMBL7999780 | 0.88 | KDM4E (0.39) | HSD11B1KDM4EUSP2KMT2ACA12 | |
| SCHEMBL8007957 | 0.86 | ALDH1A1 (0.41) | HSD11B1KDM4EUSP2KMT2ACA12 | |
| SCHEMBL2744207 | 0.85 | HSD11B1 (0.43) | HSD11B1KDM4EUSP2KMT2ACA12 | |
| SCHEMBL8014575 | 0.82 | HSD11B1 (0.38) | HSD11B1KDM4EUSP2KMT2ACA12 | |
| SCHEMBL8010715 | 0.82 | CA12 (0.40) | HSD11B1KDM4EUSP2KMT2ACA12 | |
| SCHEMBL7998459 | 0.81 | CA1 (0.38) | HSD11B1KDM4EUSP2KMT2ACA12 | |
| SCHEMBL8008055 | 0.81 | FLT1 (0.41) | HSD11B1KMT2APTGESPTGS2ALPL | |
| SCHEMBL8011292 | 0.81 | KMT2A (0.41) | HSD11B1KDM4EUSP2KMT2ACA12 | |
| SCHEMBL8009035 | 0.81 | HSD11B1 (0.36) | HSD11B1KDM4EUSP2KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165668-A | N-[2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)-2-cyanoacetyl]benzenesulfonamide charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2000-12-26 | — | — | US | disclosed |