Sugi Predict

Sugi Predict / Compounds / SCHEMBL2744207

SCHEMBL2744207

SCHEMBL2744207

N#CC(C(=O)NS(=O)(=O)c1ccccc1)=C1NS(=O)(=O)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 1/20 0.43
▸ KDM4E B2RXH2 3/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ CA12 O43570 1/20 0.39
▸ USP2 O75604 1/20 0.39
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ BCHE P06276 1/20 0.39
▸ CA4 P22748 1/20 0.39
▸ CA6 P23280 1/20 0.39
▸ CA5A P35218 1/20 0.39
▸ CA7 P43166 1/20 0.39
▸ CA9 Q16790 1/20 0.39
▸ CA14 Q9ULX7 1/20 0.39
▸ CA5B Q9Y2D0 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.36
▸ GAA P10253 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ PTGES O14684 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8014575 0.92 HSD11B1 (0.38) HSD11B1KDM4EKMT2ACA12USP2
SCHEMBL8011292 0.91 KMT2A (0.41) HSD11B1KDM4EKMT2ACA12USP2
SCHEMBL8008055 0.91 FLT1 (0.41) HSD11B1KMT2AMAPTPTGESALPL
SCHEMBL7998459 0.91 CA1 (0.38) HSD11B1KDM4EKMT2ACA12USP2
SCHEMBL8007957 0.91 ALDH1A1 (0.41) HSD11B1KDM4EKMT2ACA12USP2
SCHEMBL7998786 0.89 HSD11B1 (0.36) HSD11B1KDM4EKMT2ACA12USP2
SCHEMBL8010715 0.89 CA12 (0.40) HSD11B1KDM4EKMT2ACA12USP2
SCHEMBL8009035 0.88 HSD11B1 (0.36) HSD11B1KDM4EKMT2ACA12USP2
SCHEMBL8008194 0.88 FBP1 (0.41) KDM4EKMT2APTGESALPIPTGS2
SCHEMBL7998835 0.88 GAA (0.39) HSD11B1KMT2ACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178274-B2 Toner process XEROX CORPORATION (US) 2012-05-15 — — US claimed
US-20100015544-A1 TONER PROCESS XEROX CORPORATION (US) 2010-01-21 — — US claimed
US-6165668-A N-[2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)-2-cyanoacetyl]benzenesulfonamide charge control agents for electrostatographic toners and developers EASTMAN KODAK COMPANY (US) 2000-12-26 — — US claimed
EP-2253999-B1 TONER COMPOSITIONS XEROX CORP (US) 2018-07-11 — — EP disclosed
US-8197998-B2 Toner compositions XEROX CORPORATION (US) 2012-06-12 — — US disclosed
US-8178274-B2 Toner process XEROX CORPORATION (US) 2012-05-15 — — US disclosed
US-20100297546-A1 TONER COMPOSITIONS XEROX CORPORATION (US) 2010-11-25 — — US disclosed
EP-2253999-A2 Toner compositions Xerox Corporation (US) 2010-11-24 — — EP disclosed
US-20100015544-A1 TONER PROCESS XEROX CORPORATION (US) 2010-01-21 — — US disclosed
US-6165668-A N-[2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)-2-cyanoacetyl]benzenesulfonamide charge control agents for electrostatographic toners and developers EASTMAN KODAK COMPANY (US) 2000-12-26 — — US disclosed
US-6165668-A N-[2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)-2-cyanoacetyl]benzenesulfonamide charge control agents for electrostatographic toners and developers EASTMAN KODAK COMPANY (US) 2000-12-26 — — US disclosed
US-6165668-A N-[2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)-2-cyanoacetyl]benzenesulfonamide charge control agents for electrostatographic toners and developers EASTMAN KODAK COMPANY (US) 2000-12-26 — — US disclosed