Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 7/20 | 0.41 |
| ▸ | FLT4 | P35916 | 7/20 | 0.41 |
| ▸ | KDR | P35968 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2744207 | 0.91 | HSD11B1 (0.43) | PTGS2PTGESALPLALPIKMT2A | |
| SCHEMBL8014575 | 0.90 | HSD11B1 (0.38) | PTGS2PTGESALPLALPIMEN1 | |
| SCHEMBL7998459 | 0.89 | CA1 (0.38) | PTGESKMT2AHSD11B1MAPT | |
| SCHEMBL8007957 | 0.89 | ALDH1A1 (0.41) | L3MBTL1PTGS2PTGESKMT2APTGS1 | |
| SCHEMBL8011292 | 0.89 | KMT2A (0.41) | L3MBTL1PTGESALPLMEN1KMT2A | |
| SCHEMBL8008194 | 0.89 | FBP1 (0.41) | FLT1FLT4KDRPTGS2PTGES | |
| SCHEMBL8010715 | 0.87 | CA12 (0.40) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL7998786 | 0.87 | HSD11B1 (0.36) | PTGESALPLALPIMEN1KMT2A | |
| SCHEMBL8009035 | 0.86 | HSD11B1 (0.36) | PTGESALPLALPIMEN1KMT2A | |
| SCHEMBL7998835 | 0.86 | GAA (0.39) | FLT1FLT4KDRL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165668-A | N-[2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)-2-cyanoacetyl]benzenesulfonamide charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2000-12-26 | — | — | US | disclosed |