Prednisolone Acetate

Prednisolone Acetate

SCHEMBL7999

CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

NR3C1

The experimentally established mechanism targets of Prednisolone Acetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 known ✓ P04150 9/20 0.78
HIF1A Q16665 6/20 1.00
PGR P06401 6/20 1.00
CYP3A4 P08684 4/20 0.78
AR P10275 3/20 0.78
HSD17B10 Q99714 2/20 0.78
SERPINA6 P08185 2/20 0.78
ABCB11 O95342 1/20 0.78
TNF P01375 1/20 0.78
IL6 P05231 1/20 0.78
NR3C2 P08235 1/20 0.78
GLUL P15104 1/20 0.78
ADAM17 P78536 1/20 0.78
GPBAR1 Q8TDU6 1/20 0.78
CYP2C19 P33261 1/20 0.78
LMNA P02545 4/20 0.78
F2 P00734 1/20 0.73
KMT2A Q03164 2/20 0.71
CHRM1 P11229 1/20 0.71
USP2 O75604 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prednisolone Acetate SCHEMBL13044467 1.00 HIF1A (1.00) HIF1APGRNR3C1CYP3A4AR
Prednisolone Acetate SCHEMBL8000 1.00 HIF1A (1.00) HIF1APGRNR3C1CYP3A4AR
Prednisolone Acetate SCHEMBL10118889 1.00 HIF1A (1.00) HIF1APGRNR3C1CYP3A4AR
Prednisolone Acetate SCHEMBL9806574 0.97 HIF1A (0.93) HIF1APGRNR3C1CYP3A4AR
Prednisolone Acetate SCHEMBL9806568 0.97 HIF1A (0.93) HIF1APGRNR3C1CYP3A4AR
Prednisolone Acetate SCHEMBL9838659 0.93 HIF1A (0.86) HIF1APGRNR3C1CYP3A4AR
SCHEMBL14867443 0.92 HIF1A (0.85) HIF1APGRNR3C1CYP3A4AR
SCHEMBL9426742 0.92 PGR (0.85) HIF1APGRNR3C1CYP3A4AR
SCHEMBL16009510 0.92 HIF1A (0.91) HIF1APGRNR3C1CYP3A4AR
SCHEMBL4537969 0.91 HIF1A (0.84) HIF1APGRNR3C1CYP3A4AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13248 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115166-A1 COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF PHOTORECEPTOR ROD DEGENERATIONS AND GENERATION OF PHOTORECEPTORS PURDUE RESEARCH FOUNDATION (US) 2026-04-30 US claimed
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
CN-121586586-A Process for preparing ophthalmic compositions of low solubility materials 全福生物科技股份有限公司 2026-02-27 CN claimed
EP-4692785-A1 PREPARATION LIQUID FOR ANALYZING HEMOGLOBIN COMPONENT, AND METHOD FOR MEASURING HEMOGLOBIN COMPONENT Tosoh Corporation (JP) 2026-02-11 EP claimed
EP-4676597-A2 RIPASUDIL BASED OPHTHALMIC TREATMENTS Kowa Company, Ltd. (US) 2026-01-14 EP claimed
US-20250268918-A1 METHODS FOR MAKING REDUCED PARTICLE SIZE COMPOUNDS TAP PHARMACEUTICALS, AG (CH) 2025-08-28 US claimed
US-20250268824-A1 METHODS FOR MAKING REDUCED PARTICLE SIZE COMPOUNDS TAP PHARMACEUTICALS AG (CH) 2025-08-28 US claimed
US-20250268474-A1 Systems and Methods for Detecting Fibrosis 3HELIX, INC. (US) 2025-08-28 US claimed
US-20250242092-A1 SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS SIO2 MEDICAL PRODUCTS INC (US) 2025-07-31 US claimed
EP-4590283-A1 MUCOADHESIVE DRUG DELIVERY SYSTEMS AND METHODS OF USE Madd Ophthalmics Ltd. (CA) 2025-07-30 EP claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed
US-4304765-A Ocular insert housing steroid in two different therapeutic forms ALZA CORPORATION (US) 1981-12-08 US claimed
US-4271143-A ACRYLIC POLYMER GEL ALCON LABORATORIES, INC. (US) 1981-06-02 US claimed
US-4244942-A Creamy preparation containing steroid and process for the preparation thereof TOKO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1981-01-13 US claimed
US-4136173-A VEHICLES FOR OPHTHALMIC DRUGS AMERICAN HOME PRODUCTS CORP. (US) 1979-01-23 US claimed
US-4115544-A DRUG PARTICLES MIXED WITH RELEASE RATE-CONTROLLING HOMOPOLYMER ALZA CORPORATION (US) 1978-09-19 US claimed
US-4014335-A Ocular drug delivery device ALZA CORPORATION (US) 1977-03-29 US claimed
US-4001388-A POLYESTERS ALZA CORPORATION (US) 1977-01-04 US claimed
US-3962414-A Structured bioerodible drug delivery device ALZA CORPORATION (US) 1976-06-08 US claimed
US-3962430-A Sterilization of solid non-electrolyte medicinal agents employing sodium chloride MERCK & CO., INC. (US) 1976-06-08 US claimed