SCHEMBL7999005

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7998217	0.95	AVPR1A (0.41)	HDAC3HDAC2HIF1ANAMPTAVPR1A
	SCHEMBL1497010	0.94	HIF1A (0.39)	HDAC3HDAC2HIF1APOLBTSHR
	SCHEMBL7999342	0.92	POLB (0.46)	HIF1APOLBTSHRNAMPTALDH1A1
	SCHEMBL4223063	0.91	HDAC1 (0.43)	HDAC3HDAC2HIF1APOLBTSHR
	SCHEMBL8000939	0.91	KCNH2 (0.36)	HDAC3HDAC2HIF1AUSP25USP28
	SCHEMBL1497140	0.89	HDAC1 (0.41)	HIF1AUSP28NAMPTHDAC1LMNA
	SCHEMBL9915276	0.88	IDO1 (0.40)	HDAC2HDAC1
	SCHEMBL1496886	0.88	AVPR1A (0.42)	HDAC3HDAC2TSHRAVPR1A
	SCHEMBL1496919	0.88	SIGMAR1 (0.41)	HIF1APOLBTSHRNAMPTALDH1A1
	SCHEMBL1497201	0.87	NAMPT (0.45)	POLBTSHRNAMPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.