SCHEMBL1496919

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496941	0.96	SIGMAR1 (0.43)	SIGMAR1NAMPTSUCNR1DRD2ACKR3
	SCHEMBL1496917	0.95	SIGMAR1 (0.40)	SIGMAR1NAMPTSUCNR1DRD2ACKR3
	SCHEMBL3224387	0.95	SIGMAR1 (0.42)	SIGMAR1NAMPTSUCNR1DRD2POLB
	SCHEMBL8001525	0.93	POLB (0.42)	SIGMAR1NAMPTPOLBTSHRKDM4E
	SCHEMBL8001966	0.92	ACHE (0.36)	SIGMAR1NAMPTSUCNR1HIF1ACTSL
	SCHEMBL1497012	0.91	SIGMAR1 (0.42)	SIGMAR1NAMPTSUCNR1DRD2ACKR3
	SCHEMBL3223286	0.91	SIGMAR1 (0.45)	SIGMAR1NAMPTSUCNR1DRD2ACKR3
	SCHEMBL1496985	0.89	USP2 (0.45)	SIGMAR1NAMPTPOLBTSHR
	SCHEMBL1496980	0.89	SIGMAR1 (0.40)	SIGMAR1ACKR3AVPR1A
	SCHEMBL9915261	0.89	ALK (0.37)	CSF1RFLT3ALDH1A1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.