Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19043653 | 0.88 | SIGMAR1 (0.55) | HRH3SIGMAR1EBPTMEM97 | |
| SCHEMBL19904416 | 0.86 | ABCB1 (0.44) | L3MBTL1HRH3SIGMAR1DRD2SLC6A4 | |
| SCHEMBL19904406 | 0.85 | HRH3 (0.48) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL19904479 | 0.85 | HRH3 (0.45) | HRH3SIGMAR1DRD2SLC6A4SLC6A3 | |
| SCHEMBL19904510 | 0.82 | ABCB1 (0.43) | L3MBTL1HRH3SIGMAR1DRD2SLC6A4 | |
| SCHEMBL19043072 | 0.81 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1KDM4EHRH3SIGMAR1 | |
| SCHEMBL19904585 | 0.80 | SIGMAR1 (0.40) | L3MBTL1HRH3SIGMAR1DRD2SLC6A4 | |
| SCHEMBL20382554 | 0.80 | HRH1 (0.53) | HRH3SIGMAR1DRD2SLC6A4SLC6A3 | |
| SCHEMBL26015673 | 0.80 | SIGMAR1 (0.48) | L3MBTL1ALDH1A1KDM4EHRH3SIGMAR1 | |
| SCHEMBL20631739 | 0.76 | SIGMAR1 (0.47) | HRH3SIGMAR1DRD2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117150-A2 | METHOD OF TREATING LUPUS WITH CERAMIDE DERIVATIVES | GENZYME CORPORATION (US) | 2009-09-24 | — | — | WO | disclosed |