SCHEMBL7999214

SCHEMBL7999214

C=C(C)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.52
PLA2G2A P14555 1/20 0.47
PLA2G5 P39877 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
FPR2 P25090 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
CA2 P00918 2/20 0.37
CA1 P00915 1/20 0.37
MAPK1 P28482 1/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
SLC7A5 Q01650 1/20 0.36
RXFP1 Q9HBX9 1/20 0.35
MME P08473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7999217 1.00 TGFBR1 (0.52) TGFBR1PLA2G2APLA2G5SMN1; SMN2ALDH1A1
SCHEMBL8184931 0.85 TGFBR1 (0.50) TGFBR1PLA2G2APLA2G5ALDH1A1CA2
SCHEMBL8184915 0.85 TGFBR1 (0.50) TGFBR1PLA2G2APLA2G5ALDH1A1CA2
SCHEMBL597201 0.82 PLA2G2A (0.50) PLA2G2APLA2G5SMN1; SMN2ALDH1A1LMNA
SCHEMBL597203 0.82 PLA2G2A (0.50) PLA2G2APLA2G5SMN1; SMN2ALDH1A1LMNA
SCHEMBL8151776 0.81 TGFBR1 (0.50) TGFBR1PLA2G2APLA2G5SMN1; SMN2ALDH1A1
SCHEMBL8375421 0.81 TGFBR1 (0.41) TGFBR1PLA2G2APLA2G5ALDH1A1POLB
SCHEMBL8184467 0.80 ALDH1A1 (0.58) TGFBR1PLA2G2APLA2G5ALDH1A1FPR2
SCHEMBL8184466 0.80 ALDH1A1 (0.58) TGFBR1PLA2G2APLA2G5ALDH1A1FPR2
SCHEMBL13137798 0.79 PLA2G2A (0.52) PLA2G2APLA2G5SMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000069394-A1 ONE-PART FLUORIDE RELEASING DENTAL MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-11-23 WO claimed
CN-114096560-B Sugar purification 默克专利股份公司 2025-06-13 CN disclosed
CN-114007737-B Antibody drug conjugate purification 默克专利股份公司 2024-07-05 CN disclosed
CN-114096560-A Purification of sugar forms 默克专利股份公司 2022-02-25 CN disclosed
CN-114007737-A Antibody drug conjugate purification 默克专利股份公司 2022-02-01 CN disclosed
WO-2000069394-A1 ONE-PART FLUORIDE RELEASING DENTAL MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-11-23 WO disclosed
EP-0874868-A4 THERMOREVERSIBLE HYDROGELS COMPRISING LINEAR COPOLYMERS AND THEIR USE IN ELECTROPHORESIS ACLARA BIOSCIENCES INC (US) 2000-07-12 EP disclosed
US-6046289-A FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS FUJIFILM CORPORATION (JP) 2000-04-04 US disclosed
US-5883211-A Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis ACLARA BIOSCIENCES, INC. (US) 1999-03-16 US disclosed
EP-0874868-A1 THERMOREVERSIBLE HYDROGELS COMPRISING LINEAR COPOLYMERS AND THEIR USE IN ELECTROPHORESIS Aclara Biosciences, Inc. (US) 1998-11-04 EP disclosed
WO-1997040078-A1 THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS SOANE BIOSCIENCES (US) 1997-10-30 WO disclosed
WO-1997026288-A1 THERMOREVERSIBLE HYDROGELS COMPRISING LINEAR COPOLYMERS AND THEIR USE IN ELECTROPHORESIS ACLARA BIOSCIENCES, INC. (US) 1997-07-24 WO disclosed
US-5631337-A Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis SOANE BIOSCIENCE (US) 1997-05-20 US disclosed
EP-0488258-B1 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO LTD (JP) 1996-04-17 EP disclosed
US-5175254-A Solid phase peptide synthesis using a polyacrylic support in aqueous solution SOCIETE D'EXPANSION SCIENTIFQUE EXPANSIA (FR) 1992-12-29 US disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed