SCHEMBL7999217

SCHEMBL7999217

C=C(C)C(=O)NC(C(=O)O)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.52
PLA2G2A P14555 1/20 0.47
PLA2G5 P39877 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.42
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
FPR2 P25090 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
CA2 P00918 2/20 0.37
CA1 P00915 1/20 0.37
MAPK1 P28482 1/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
SLC7A5 Q01650 1/20 0.36
RXFP1 Q9HBX9 1/20 0.35
MME P08473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7999214 1.00 TGFBR1 (0.52) TGFBR1PLA2G2APLA2G5SMN1; SMN2ALDH1A1
SCHEMBL8184931 0.85 TGFBR1 (0.50) TGFBR1PLA2G2APLA2G5ALDH1A1CA2
SCHEMBL8184915 0.85 TGFBR1 (0.50) TGFBR1PLA2G2APLA2G5ALDH1A1CA2
SCHEMBL597201 0.82 PLA2G2A (0.50) PLA2G2APLA2G5SMN1; SMN2ALDH1A1LMNA
SCHEMBL597203 0.82 PLA2G2A (0.50) PLA2G2APLA2G5SMN1; SMN2ALDH1A1LMNA
SCHEMBL8151776 0.81 TGFBR1 (0.50) TGFBR1PLA2G2APLA2G5SMN1; SMN2ALDH1A1
SCHEMBL8375421 0.81 TGFBR1 (0.41) TGFBR1PLA2G2APLA2G5ALDH1A1POLB
SCHEMBL8184467 0.80 ALDH1A1 (0.58) TGFBR1PLA2G2APLA2G5ALDH1A1FPR2
SCHEMBL8184466 0.80 ALDH1A1 (0.58) TGFBR1PLA2G2APLA2G5ALDH1A1FPR2
SCHEMBL13137798 0.79 PLA2G2A (0.52) PLA2G2APLA2G5SMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103897106-B Method for improving grafting rate of polyolefin grafted unsaturated carboxylic acid monomer 哈尔滨工程大学 2016-06-29 CN claimed
CN-103224593-B A kind of method of linear low density polyethylene grafting of polar monomers HARBIN ENGINEERING UNIV. (CN) 2015-12-09 CN claimed
CN-103232575-A Preparation method for solid unsaturated carboxylic acid-functionalized linear low density polyethylene UNIV HARBIN ENG 2013-08-07 CN claimed
CN-103224593-A Method for grafting linear low density polyethylene to polar monomer UNIV HARBIN ENG 2013-07-31 CN claimed
WO-2000069394-A1 ONE-PART FLUORIDE RELEASING DENTAL MATERIALS 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-11-23 WO claimed
CN-114096560-B Sugar purification 默克专利股份公司 2025-06-13 CN disclosed
CN-114007737-B Antibody drug conjugate purification 默克专利股份公司 2024-07-05 CN disclosed
US-11712404-B2 Methacrylamide adhesive systems UNIV OREGON HEALTH & SCIENCE (US) 2023-08-01 US disclosed
US-11712404-B2 Methacrylamide adhesive systems UNIV OREGON HEALTH & SCIENCE (US) 2023-08-01 US disclosed
CN-114096560-A Purification of sugar forms 默克专利股份公司 2022-02-25 CN disclosed
US-20210047450-A1 METHACRYLAMIDE ADHESIVE SYSTEMS UNIV OREGON HEALTH & SCIENCE (US) 2021-02-18 US disclosed
WO-2019173080-A1 METHACRYLAMIDE ADHESIVE SYSTEMS OREGON HEALTH & SCIENCE UNIVERSITY (US) 2019-09-12 WO disclosed
WO-1997040078-A1 THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS SOANE BIOSCIENCES (US) 1997-10-30 WO disclosed
WO-1997026288-A1 THERMOREVERSIBLE HYDROGELS COMPRISING LINEAR COPOLYMERS AND THEIR USE IN ELECTROPHORESIS ACLARA BIOSCIENCES, INC. (US) 1997-07-24 WO disclosed
US-5631337-A Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis SOANE BIOSCIENCE (US) 1997-05-20 US disclosed
EP-0488258-B1 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO LTD (JP) 1996-04-17 EP disclosed
EP-0488258-A2 Propenamide derivatives, polymers, copolymers and use thereof FUJI PHOTO FILM CO., LTD. (JP) 1992-06-03 EP disclosed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210047450-A1 METHACRYLAMIDE ADHESIVE SYSTEMS ECPAS, CAD, ILK TGFBR1 2475/4885PLA2G2A 2281/4885PLA2G5 3178/4885
US-11712404-B2 Methacrylamide adhesive systems ECPAS, CAD, ILK TGFBR1 2475/4885PLA2G2A 2281/4885PLA2G5 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.