Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629468 | 0.93 | MEN1 (0.38) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL8049546 | 0.84 | LMNA (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL629459 | 0.74 | DGKA (0.51) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL3482987 | 0.73 | GPR84 (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| 1,6-Hexanediol SCHEMBL5189109 | 0.72 | KDM4E (0.66) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Glyceryl Monostearate SCHEMBL27413753 | 0.70 | LMNA (0.80) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL30327194 | 0.69 | TSHR (0.47) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL990662 | 0.69 | KDM4E (0.53) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL30099173 | 0.68 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL1695888 | 0.68 | KDM4E (0.63) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011609-A4 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-1011609-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998050005-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |