SCHEMBL990662

SCHEMBL990662

CCCCCCCCCC(=O)C(CCCCCCC)C(C(=O)CCCCCCCCC)(C(=O)CCCCCCCCC)C(=O)OCC(O)CO

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
DUSP3 P51452 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
LMNA P02545 1/20 0.53
DGKA P23743 1/20 0.47
FAAH O00519 4/20 0.40
FFAR4 Q5NUL3 1/20 0.38
USP2 O75604 1/20 0.38
FFAR1 O14842 1/20 0.38
CNR2 P34972 1/20 0.37
LPAR6 P43657 1/20 0.37
LPAR1 Q92633 1/20 0.37
LPAR4 Q99677 1/20 0.37
LPAR5 Q9H1C0 1/20 0.37
LPAR2 Q9HBW0 1/20 0.37
LPAR3 Q9UBY5 1/20 0.37
ENPP2 Q13822 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28858183 0.82 MEN1 (0.65) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL8049546 0.79 LMNA (0.50) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL10342924 0.78 DGKA (0.59) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL15876497 0.78 FFAR1 (0.40) KDM4EDUSP3MEN1KMT2AFFAR4
SCHEMBL7524306 0.77 KDM4E (0.61) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL6563475 0.77 KDM4E (0.61) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL15796306 0.76 KDM4E (0.60) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL15876486 0.76 KDM4E (0.60) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL17003743 0.75 KDM4E (0.63) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL20819044 0.75 KDM4E (0.63) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130210921-A1 Method for Giving Warmth to Skin ROHTO PHARMACEUTICAL CO., LTD. (JP) 2013-08-15 US claimed
WO-2023152656-A2 NOVEL HIGHLY SUSTAINABLE COMPOSITIONS FOR MODULATION OF GENE EXPRESSION IN HUMAN SKIN, AND METHODS OF PRODUCTION THEREOF Visolis Technologies, Inc. (US) 2023-08-17 WO disclosed
US-20230248677-A1 NOVEL HIGHLY SUSTAINABLE COMPOSITIONS FOR MODULATION OF GENE EXPRESSION IN HUMAN SKIN, AND METHODS OF PRODUCTION THEREOF Visolis, Inc. 2023-08-10 US disclosed
WO-2022260147-A1 ADDITIVE FOR COSMETIC COMPOSITION Spiber株式会社 2022-12-15 WO disclosed
US-10874604-B2 Cosmetic composition or external composition, and cosmetic raw material composition DOW TORAY CO., LTD. (JP) 2020-12-29 US disclosed
EP-2905319-B1 SURFACE TREATMENT AGENT FOR POWDERS CONTAINING A CO-MODIFIED ORGANOPOLYSILOXANE AND COSMETIC COMPOSITIONS COMPRISING IT DOW TORAY CO LTD (JP) 2020-09-30 EP disclosed
US-20200038312-A1 COSMETIC COMPOSITION OR EXTERNAL COMPOSITION, AND COSMETIC RAW MATERIAL COMPOSITION DOW TORAY CO., LTD. (JP) 2020-02-06 US disclosed
EP-3524228-A1 COSMETIC COMPOSITION OR EXTERNAL COMPOSITION, AND COSMETIC RAW MATERIAL COMPOSITION Dow Silicones Corporation (US) 2019-08-14 EP disclosed
EP-2797992-B1 DIGLYCERIN DERIVATE-MODIFIED SILICONE, EMULSIFIER FOR WATER-IN-OIL EMULSION USING THE SAME, EXTERNAL USE PREPARATION, AND COSMETIC COMPOSITION DOW CORNING TORAY CO LTD (JP) 2019-04-17 EP disclosed
US-10172779-B2 Copolymer having carbosiloxane dendrimer structure and composition and cosmetic containing the same DOW CORNING TORAY CO., LTD. (JP) 2019-01-08 US disclosed
WO-2013100169-A1 CO-MODIFIED ORGANOPOLYSILOXANE, EMULSIFIER FOR WATER-IN-OIL EMULSION, EXTERNAL USE PREPARATION, AND COSMETIC COMPOSITION USING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2013-07-04 WO disclosed
US-20110027326-A1 External Composition for Skin ROHTO PHARMACEUTICAL CO., LTD. (JP) 2011-02-03 US disclosed
EP-2269652-A1 COMPOSITION FOR EXTERNAL APPLICATION TO SKIN Rohto Pharmaceutical Co., Ltd. (JP) 2011-01-05 EP disclosed
US-20080293673-A1 N-ACETYGLUCOSAMINE DERIVATIVES AND USE THEREOF KAO CORPORATION 2008-11-27 US disclosed
US-7393937-B2 N-acetylglucosamine derivatives and use thereof KAO CORPORATION (JP) 2008-07-01 US disclosed
US-20080118538-A1 OIL DISPERSION OF POWDER BEING SURFACE-TREATED WITH SPECIFIC HALF ESTER OIL, AND COSMETIC COMPOSITION CONTAINING THE SAME MIYOSHI KASEI, INC. (JP) 2008-05-22 US disclosed
EP-1881039-A1 OIL DISPERSION OF POWDER BEING SURFACE-TREATED WITH SPECIFIC ACIDIC ESTER OIL, AND COSMETIC COMPOSITION CONTAINING THE SAME Miyoshi Kasei, Inc. (JP) 2008-01-23 EP disclosed
US-20070265347-A1 ENCAPSULATED OIL-IN-WATER TYPE EMULSION COMPOSITION AJINOMOTO CO. INC (JP) 2007-11-15 US disclosed
US-20060020127-A1 N-acetylglucosamine derivatives and use thereof KANEBO COSMETICS INC. (JP) 2006-01-26 US disclosed
EP-1553101-A1 N-ACETYLGLUCOSAMINE DERIVATIVES AND USE THEREOF Kanebo Cosmetics Inc. (JP) 2005-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020127-A1 N-acetylglucosamine derivatives and use thereof FUT6, B3GNT2, FUT5 KDM4E 3685/4885DUSP3 4055/4885MEN1 2557/4885
US-20070265347-A1 ENCAPSULATED OIL-IN-WATER TYPE EMULSION COMPOSITION AGPAT2, GPR18, AGPAT5 KDM4E 2766/4885DUSP3 4875/4885MEN1 1905/4885
US-10874604-B2 Cosmetic composition or external composition, and cosmetic raw material composition H1-0, CUTA, HAO2 KDM4E 3216/4885DUSP3 4879/4885MEN1 2456/4885
US-10172779-B2 Copolymer having carbosiloxane dendrimer structure and composition and cosmetic containing the same DCLRE1A, MC1R, ADGRE5 KDM4E 4508/4885DUSP3 4775/4885MEN1 1552/4885
US-20200038312-A1 COSMETIC COMPOSITION OR EXTERNAL COMPOSITION, AND COSMETIC RAW MATERIAL COMPOSITION H1-0, CUTA, HAO2 KDM4E 3216/4885DUSP3 4879/4885MEN1 2456/4885
US-20080293673-A1 N-ACETYGLUCOSAMINE DERIVATIVES AND USE THEREOF B3GNT2, FUT6, FUT5 KDM4E 3795/4885DUSP3 3959/4885MEN1 2678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.