Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999664 | 0.93 | MAOB (0.36) | ADRA2APPARGPPARACASRMAOB | |
| SCHEMBL8001061 | 0.92 | ADRA2A (0.41) | ADRA2AHDAC11HDAC8PPARGPPARD | |
| SCHEMBL7998987 | 0.90 | ADRA2A (0.38) | ADRA2AHDAC11HDAC8L3MBTL1APAF1 | |
| SCHEMBL8002068 | 0.88 | ADRA2A (0.40) | ADRA2ACASRL3MBTL1APAF1MAOB | |
| SCHEMBL8001337 | 0.86 | ALOX15 (0.38) | MAPTMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL8001330 | 0.86 | ALOX15 (0.38) | MAPTMEN1ALDH1A1HPGDTSHR | |
| SCHEMBL8079821 | 0.85 | ADRA2A (0.43) | ADRA2AHDAC11HDAC8PSEN1PSEN2 | |
| SCHEMBL8004450 | 0.85 | ADRA2A (0.43) | ADRA2AHDAC11HDAC8PSEN1PSEN2 | |
| SCHEMBL8002087 | 0.85 | TP53 (0.33) | L3MBTL1MAPTTP53GAASMN1; SMN2 | |
| SCHEMBL8000745 | 0.84 | ADRA2A (0.44) | ADRA2AHDAC11HDAC8L3MBTL1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |