Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27419910 | 0.84 | ALDH1A1 (0.53) | CYP2D6TSHRMAPTALDH1A1POLB | |
| SCHEMBL20214949 | 0.83 | KMT2A (0.50) | BCHECYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL8000103 | 0.83 | NPC1 (0.56) | BCHECYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL27405685 | 0.82 | VNN1 (0.53) | ALDH1A1POLBKMT2ALMNAHDAC8 | |
| SCHEMBL913728 | 0.77 | TDP1 (0.69) | PBRM1CYP2C9CYP2C19ADRB2ADRB1 | |
| SCHEMBL8395188 | 0.77 | HDAC6 (0.69) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL10634552 | 0.76 | CYP19A1 (0.44) | CYP1A2CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL11796895 | 0.76 | PBRM1 (0.52) | PBRM1LOXL2ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL8669502 | 0.76 | TDP1 (0.67) | PBRM1CYP2C9CYP2C19ADRB2ADRB1 | |
| SCHEMBL27354565 | 0.75 | ALDH1A1 (0.71) | PBRM1TSHRADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |